Škodlivé učinky česneku?

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Neregistrovaný uživatel

13.4.2006 07:48
Neregistrovaný uživatel

XXX.XXX.88.178

Jaké mohou být škodlivé učinky při dlouhodobém podávání česneku?

Neregistrovaný uživatel

13.4.2006 10:08
Neregistrovaný uživatel

XXX.XXX.13.21

Neregistrovaný uživatel napsal(a):
Jaké mohou být škodlivé učinky při dlouhodobém podávání česneku?

Ach jo, a co takhle použít vyhledavač, co třeba tam zadat "česnek", od čeho tu je že se tu věci řeší pořád dokola?

Sáhodlouze se to řešilo už tady
https://www.ifauna.cz/diskuse/vypis.php?thema=212957&o=13#213878

A ta jedna slavná studie se 4mi koňmi okolo které se to všechno točí je k nalezení zde. Přeložené je to ve výše zmiňované diskuzi na ifauně.

http://avmajournals.avma.org/doi/abs/10.2460/ajvr.2005.66.457



Abstract
American Journal of Veterinary Research
March 2005, Vol. 66, No. 3, Pages 457-465
doi: 10.2460/ajvr.2005.66.457

Association of maximum voluntary dietary intake of freeze-dried garlic with Heinz body anemia in horses

Wendy Pearson, MScHerman J. Boermans, PhDWilliam J. Bettger, PhDBrian W. McBride, PhD Michael I. Lindinger, PhD
Department of Animal and Poultry Science, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Pearson, McBride); Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Boermans); Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Bettger, Lindinger)

Objective—To characterize hematologic and clinical consequences of chronic dietary consumption of freeze-dried garlic at maximum voluntary intake in horses.

Animals—4 healthy sex- and age-matched horses.

Procedure—An initial garlic dose (0.05 g/kg, twice daily) was fed to 2 horses in a molasses carrier as part of their normal ration and was gradually increased to maximum voluntary intake (0.25 g/kg, twice daily) over 41 days. Dietary supplementation then continued for a total of 71 days. Two control horses were fed molasses with no garlic with their ration. Blood samples were collected weekly and analyzed for hematologic and biochemical changes, including the presence of Heinz bodies. Recovery of affected blood values was followed for 5 weeks after termination of dietary supplementation with garlic.

Results—At a daily dose of > 0.2 g/kg, horses fed garlic developed hematologic and biochemical indications of Heinz body anemia, as characterized by increases in Heinz body score (HBS), mean corpuscular volume (MCV), mean corpuscular hemoglobin, platelet count, and serum unconjugated and total bilirubin concentrations and decreases in RBC count, blood hemoglobin concentration, mean corpuscular hemoglobin concentration, and serum haptoglobin concentration. Recovery from anemia was largely complete within 5 weeks after termination of dietary supplementation with garlic. Heinz body score and MCV remained high at the end of the 5-week recovery period.

Conclusions and Clinical Relevance—Horses will voluntarily consume sufficient quantities of garlic to cause Heinz body anemia. The potential for garlic toxicosis exists when horses are chronically fed garlic. Further study is required to determine the safe dietary dose of garlic in horses. (Am J Vet Res 2005;66:457–465)

Neregistrovaný uživatel

13.4.2006 11:07
Neregistrovaný uživatel

XXX.XXX.34.91

Neregistrovaný uživatel napsal(a):
Ach jo, a co takhle použít vyhledavač, co třeba tam zadat "česnek", od čeho tu je že se tu věci řeší pořád dokola?

Sáhodlouze se to řešilo už tady
https://www.ifauna.cz/diskuse/vypis.php?thema=212957&o=13#213878

A ta jedna slavná studie se 4mi koňmi okolo které se to všechno točí je k nalezení zde. Přeložené je to ve výše zmiňované diskuzi na ifauně.

http://avmajournals.avma.org/doi/abs/10.2460/ajvr.2005.66.457



Abstract
American Journal of Veterinary Research
March 2005, Vol. 66, No. 3, Pages 457-465
doi: 10.2460/ajvr.2005.66.457

Association of maximum voluntary dietary intake of freeze-dried garlic with Heinz body anemia in horses

Wendy Pearson, MScHerman J. Boermans, PhDWilliam J. Bettger, PhDBrian W. McBride, PhD Michael I. Lindinger, PhD
Department of Animal and Poultry Science, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Pearson, McBride); Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Boermans); Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1 Canada. (Bettger, Lindinger)

Objective—To characterize hematologic and clinical consequences of chronic dietary consumption of freeze-dried garlic at maximum voluntary intake in horses.

Animals—4 healthy sex- and age-matched horses.

Procedure—An initial garlic dose (0.05 g/kg, twice daily) was fed to 2 horses in a molasses carrier as part of their normal ration and was gradually increased to maximum voluntary intake (0.25 g/kg, twice daily) over 41 days. Dietary supplementation then continued for a total of 71 days. Two control horses were fed molasses with no garlic with their ration. Blood samples were collected weekly and analyzed for hematologic and biochemical changes, including the presence of Heinz bodies. Recovery of affected blood values was followed for 5 weeks after termination of dietary supplementation with garlic.

Results—At a daily dose of > 0.2 g/kg, horses fed garlic developed hematologic and biochemical indications of Heinz body anemia, as characterized by increases in Heinz body score (HBS), mean corpuscular volume (MCV), mean corpuscular hemoglobin, platelet count, and serum unconjugated and total bilirubin concentrations and decreases in RBC count, blood hemoglobin concentration, mean corpuscular hemoglobin concentration, and serum haptoglobin concentration. Recovery from anemia was largely complete within 5 weeks after termination of dietary supplementation with garlic. Heinz body score and MCV remained high at the end of the 5-week recovery period.

Conclusions and Clinical Relevance—Horses will voluntarily consume sufficient quantities of garlic to cause Heinz body anemia. The potential for garlic toxicosis exists when horses are chronically fed garlic. Further study is required to determine the safe dietary dose of garlic in horses. (Am J Vet Res 2005;66:457–465)

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